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Semaglutide is a GLP-1 receptor agonist that may be incorporated into provider-directed metabolic care plans when clinically appropriate

Melanotan-1 is sold as a research compound

Methods Trial Design Both trials were randomised, open-label, parallel-group, single-centre (Parexel, Berlin, Germany) trials (Fig

Subgroup analyses showed significant difference in FPG reduction between the exenatide group (1.02 mmol/L, 1.38 to 0.67, I 2 = 0%, P = 0.49) and sitagliptin group, and a significant reduction in liraglutide group compared to sitagliptin groups (1.14 mmol/L, 1.40 to 0.88, I 2 = 0%, P = 0.56) as well