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Liraglutide (Saxenda) NICE Technology Appraisal TA664 recommends liraglutide as an option for managing overweight and obesity in adults with a BMI of 35 kg/m or more (or 3034.9 kg/m in certain circumstances) alongside at least one weight-related comorbidity, within a specialist weight management service

The UTSW research revealed that exclusive GLP-1RA use among those treated for obesity in this age group rose from 88.2% between May and November in 2022 to 96.1% between June 2025 and January 2026

This is the central reason the GLOW protocol works: it supports multiple bottlenecks simultaneously

doi: 10.1080/13880209.2024.2351946 24