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100 mg/d HED of 1-MX (UPLEVEL, Ingenious Ingredients L.P., Lewisville, TX, USA), rat dose: 10.28 mg/kg/d) and 0.5% Carboxy Methyl Cellulose sodium were administered via oral gavage using disposable polypropylene syringes with sterilized stainless steel gavage tubes

They are structurally unrelated to the soluble GSTs and the protein family has been named MAPEG (membrane-associated proteins in eicosanoid and glutathione metabolism), since some of the members act as leukotriene C and prostaglandin E synthases ( Primary Structures and Classification of Glutathione Transferases 40 years ago scattered aminoacid sequence data were available for rodent and human GSTs