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These are thought to lead to dysfunctional neuronal pathways, abnormal synaptogenesis, neurotransmitter imbalance and neuronal connectivity [11]

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Glutathione S-transferases gene polymorphism influence on the age of diabetes type 2 onset

Thus, the conditional metabolic buffer hypothesis predicts a narrow therapeutic window in which enhancing controlled lipid utilization or improving lipid handling capacity could be beneficial, whereas indiscriminate stimulation of fatty acid oxidation may be harmful if antioxidant capacity or mitochondrial function is insufficient