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Unconjugated primary and secondary bile acids have a higher affinity for farnesoid X receptor (FXR), a key regulator found in the liver and intestines

Patients should be educated on what to look out for, such as swelling, pain, redness, and warmth in the legs for DVT, and shortness of breath, chest pain, and coughing up blood for PE

PlexusDx uses genetic data alongside clinical response to guide dose titration and treatment selection, ensuring your dose may need to go up, but your price won't

In a statement, they say in part: While we respect every healthcare professionals clinical expertise and their right to prescribe treatment based on their own medical judgement, we ask that healthcare professionals prescribe our medicines consistent with FDA-approved indications