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Whats different by week 16 that wasnt true at week 6: Clothing size changes become noticeable, often one full size down The week 4-style plateaus become less frequent as the body adjusts to a stable dose Most patients have moved to 1mg by this point, which comes with a higher chance of GI side effects if the increase happened too quickly This is typically when patients start asking whether long-term medication or a surgical option makes more sense for their remaining weight loss goals If your 6-week results were on the lower end of the range and youre projecting out to 16 weeks, its worth talking to your prescriber about whether your current trajectory will realistically get you to your goal weight, or whether its time to discuss alternatives

Your doctor will check its safe for you

Risk factors for pancreatitis on GLP-1 medications include history of pancreatitis, gallstones, high triglycerides, and heavy alcohol use

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