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on the other hand, some studies have proven that EpCAM uses the same axis for carcinogenesis

To ensure reliability, taxonomic authentication of the source plant is essential (e.g., voucher specimens, DNA barcoding) as well as chemical standardization of the extract

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Although the time course of Nrf2 stabilization and nuclear translocation indicated a rapid increase with a peak at approximately 6 h for DEM, and a slow but gradual rise triggered by NFT, maximal accumulation of Nrf2 protein, as well as the induction of GCLC and glutathione synthesis, were almost identical for both NFT and DEM after incubation periods of and beyond 24 h (Fig