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The potential for a clinic that combines GLP-1s with community, nutrition, and exercise is massive
For example, in the lungs, GLP-1s may reduce the inflammatory response, improve oxidative stress, regulate protease/anti-protease imbalance, improve airway mucus homeostasis, and reduce airway remodeling to provide benefit in patients with COPD
These agents include semaglutide (Ozempic, Wegovy), liraglutide (Victoza, Saxenda), dulaglutide (Trulicity), and tirzepatide (Mounjaro, Zepbound), which also targets the glucose-dependent insulinotropic polypeptide (GIP) receptor
In a diabetic neuropathy model in rats, liraglutide improved pain thresholds and reduced sciatic nerve damage
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