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These strategies seek to balance L-carnitines benefits with its potential risks related to TMAO production

A 2018 meta-analysis of 14 studies with over 1,000 participants found that chitosan, when paired with a calorie-restricted diet and exercise, led to a modest weight loss of about 1 kg over several weeks compared to a placebo group, which actually gained 1.5 kg in some cases

At first the bodies of vegetarians and vegans did not produce much TMAO even when they took supplements, but after a few weeks they did, Hazens team reported in the Journal of Clinical Investigation . In Medical Express December 10, 2018 they reported, The findings suggest that measuring and targeting TMAO levelssomething doctors can do with a simple blood testmay be a promising new strategy for individualizing diets and helping to prevent heart disease

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