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Pituitary tumors frequently preserve responsiveness to hypophysiotropic factors, including dopamine (DA) and somatostatin (SS), ubiquitous peptides that physiologically inhibit hormone secretion and cell proliferation at both the pituitary and the periphery levels, and thus are considered as molecules with therapeutical potential ( The inhibitory actions of DA in pituitary tumors are mediated by DA receptor subtype 2 (DRD2) [reviewed in Ref

102104,109 It is worth noting that JS-K works synergistically with chemotherapy drugs, such as cytarabine, 98 bortezomib, 95 cisplatin, and arsenic

Key contraindications may include hypersensitivity to peptides, active malignancy and unmonitored self-medication

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