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Initially, these medications were developed for the treatment of type 2 diabetes mellitus, but GLP-1 RA drugs have demonstrated remarkable outcomes in clinical settings

Semaglutide GLP-1 (Ozempic, Wegovy) and Zepbound ( tirzepatide ) are two of the most discussed medications for weight loss, and many of our patients inquire about their long-term safety

After the exclusion of 9,075 patients due to prior anti-obesity medication, and 72,731 patients for bipolar, schizophrenia, depressive disorders, anxiety and suicide ideation or attempts within 1 year before, the treatment cohort numbered 162,257 patients

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