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In patients who received background basal insulin or basal insulin plus MET, treatment with SEM 0.5 mg was associated with a statistically significant reduction in total cholesterol (treatment ratio 0.95, 95% CI 0.91 to 0.99), compared with placebo

Chen, X., He, X., Guo, Y., Liu, L., Li, H., Tan, J., Feng, W., Guan, H., Cao, X., Xiao, H., & Li, Y

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Most patients choose either early morning or early evening and maintain that schedule weekly