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Clinical trials (ten studies, 419 participants) using doses from 400 mg to 10 g over 21 days to 20 months show consistent reductions in fasting glucose, post-meal glucose, and HbA1c

TikTok might mention GLP-1 drops or oral sprays, but theres little evidence they work

But there is room for both to exist. Sowa, in fact, sells a supplement called Balanced that features many of the same ingredients as the brands discussed above, including chromium and berberine, though she is clear that she does not consider it to be a substitute for a GLP-1 prescription

Even FDA-approved patches that effectively deliver medication unlike the GLP-1 patches can cause skin irritation both from the medications and also from the patches themselves, Jay says