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Key Areas Covered What is Methylcobalamin Definition, Structure, Function What is Cyanocobalamin Definition, Structure, Function Similarities Between Methylcobalamin and Cyanocobalamin Outline of Common Features Difference Between Methylcobalamin and Cyanocobalamin Comparison with Key Differences Key Terms Cyanocobalamin, Methylcobalamin, Vitamin B12 What is Methylcobalamin Methylcobalamin is the naturally-occurring form of vitamin B12, mainly found in animal-based foods

One study, which also evaluated cognitive function in patients with high MMA concentrations, found no significant effects on the MDD inventory score, but only 30 of the 140 subjects had depression at baseline, which may have diluted any benefits

When an intramuscular injection is administered incorrectly, the damage may not always be immediate

In the 1990s and 2000s, further non-RCT studies in the elderly with or without dementia/AD and low B12 status have also mostly shown no benefit of B12 for cognitive function