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Novo Nordisk has launched two large Phase III trials (EVOKE and EVOKE+) to assess whether semaglutide can slow cognitive decline in participants with early-stage Alzheimers disease

The anti-inflammatory effects appear to be both direct and indirect

OR Your starting BMI was 30 or higher and you had at least one of the following: Heart failure with preserved ejection fraction Uncontrolled high blood pressure despite treatment with two blood pressure medications Chronic kidney disease stage 3a or higher OR Your starting BMI was 27 or higher and you had at least one of the following: Prediabetes Previous heart attack Previous stroke Symptomatic peripheral artery disease Skippack Pharmacy does not make the final eligibility decision

Older adults are also more likely to be on other medications that interact with NSAIDs