semaglutide heart failure trial VisualAbstract: Improves Outcomes in Patients with Obesity-Related and Type 2 Diabetes Cardiovascular outcomes of semaglutide and

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Although glitazone therapy can reduce cardiovascular events in selected populations [129], these agents also increase the risk of clinically apparent heart failure and of fractures [129, 130], which in turn may reduce physical function and worsen sarcopenia

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