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A 2020 review by the Journal of the International Society of Sports Nutrition (JISSN) summarized over 70 studies and found that L-carnitine supplementation: Improves muscle oxygenation during exercise Reduces exercise-induced muscle damage Enhances recovery rates after intense workouts Provides mixed results for direct weight loss, although it consistently supports fat metabolism These findings help answer the question does L-carnitine work, especially when your goal is improving performance and recovery rather than relying on it as a standalone fat-loss supplement

This variant was also associated with an increased risk of small cell lung cancer, breast cancer, and ovarian cancer (but lower than the risk associated with the BRCA pathogenic variants that decrease protein levels)

And while these drugs are powerful, there are concerns as mentioned above

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