glp-1 drugs and breast cancer Ozempic, Wegovy: Lower Risk by 30% The effect of GLP-1R agonists

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Methodological limits Many of the older clinical reports are small, are not rigorously randomized or blinded, and use surrogate biomarkers rather than hard clinical endpoints

Semaglutide enhances glucose-dependent insulin secretion from pancreatic beta cells, suppresses glucagon secretion from alpha cells, improves insulin response in peripheral tissues, and may enhance beta cell function and survival

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