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doi: 10.1016/j.heliyon.2024.e29695 468 EkawardhaniSBerbudiA

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Researchers noted that the SASP factors secreted by senescent PDAC cells included pro-angiogenic agents that contributed to increased tumor vascularization [39]

These advances will rely heavily on the integration of organ-on-chip platforms and digital twin models, enabling continuous in vitro and in silico validation of therapeutic decisions before patient application