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But that translation never happens naturally

The upstream mechanism by which this happens has been a subject of mechanistic investigation, with hypotheses ranging from direct nuclear localization of the copper complex to indirect signaling via copper-dependent enzyme activity (notably superoxide dismutase 1, SOD1) and downstream transcription factor modulation

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This approach preempts a post-surgical reduction in oocytes and maintains the high pregnancy and low miscarriage rates of the age of the patient when the embryo was created and frozen, rather than of the more advanced age when the embryo is transferred