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In summary, these results demonstrated that LC suppresses pro-inflammatory polarization in BMDMs

Topical use is often well tolerated when introduced slowly and paired with moisturizer and sunscreen

In addition, degradation within the gastrointestinal tract and first-pass metabolism substantially reduce systemic bioavailability, and preclinical animal findings may not consistently predict human pharmacokinetics and efficacy ( in vivo transformation mechanisms to meet the stringent demands for safety, stability, reproducibility, and standardization necessary for clinical translation

Animal studies involving surgically severed tendons document measurable improvements in tensile strength and tissue integrity within 14 to 21 days of administration