Additional custom lists comprised sirtuin genes and sirtuin interactors (selected in Cytoscape), as well as disease-related categories such as myocardial infarction (MI) and HF obtained from DisGenet database ( Functionally enriched sets were also designed from Gene Ontology terms, including apoptosis, coagulation, platelet activation, inflammation, hematopoiesis, angiogenesis, cardiac muscle functions, muscle hypertrophy, fibrosis, oxidative stress, senescence and aging, and hypoxia which we used in our previous studies relevant to cardiovascular disease (CVD) 95,96
Bru-seq-based transcription profiling unravelled novel roles for GSTO1 in cholesterol metabolism, oxidative and endoplasmic stress responses, cytoskeleton and cell migration
All possible dosages and forms may not be included here
The duration of treatment depends on the severity of your deficiency and your body's response