Another non-antioxidant action of vitamin C in the brain is in the reduction of metal (e.g., iron, copper) ions (44)
Due to this high aerobic demand, the generation of high amounts of ROS and other oxidative by-products is unavoidable ( GSH is synthesized via two ATP-dependent enzymatic steps catalyzed by glutamate-cysteine ligase (GCL) and glutathione synthetase
Of these many markers, few are soluble, including Fas ligand, granzyme B, soluble CD40 ligand, granulysin, serum high mobility group protein B1, serum lactate dehydrogenase, a-defensins 13 in the blisters, Bcl-2 expression in the dermal infiltrates, thymus and activation-regulated chemokine, and glutathione-S transferase-pi expression
Tuy nhin, khng t loi kem chng nng trn th trng c cha cn, d gy kh da hoc kch ng cho nhng ngi c ln da nhy cm