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Figure 2 To meet these high demands, beta-cells have an extensive ER with multiple chaperones to aid in protein folding, packaging, and secretion
Oxidative stress results in increased expression of calreticulin, Psme3, and vimentin, which regulate TGF-1-induced proliferation and epithelial-mesenchymal transition (EMT) by modulating Smad signaling 33,34
TB-500 is larger at 43 amino acids and approximately 4963 Da
If you substitute pure sterile water in a protocol that requires repeated withdrawals over several days, you run an incredibly high risk of microbial contamination
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