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While existing GLP-1 medications have shown greater weight loss than Eli Lillys oral medication, the oral option targets both weight loss and type 2 diabetes in patients

Orforglipron, the easiertouse alternative to injectable weightloss and diabetes medications, is a promising new tool with improved convenience for providers and patients

The most common are nausea, facial flushing, darkening of moles, headaches, and increased libido

In addition, in dementia with Lewy bodies (DLB), which is another form of -synucleinopathies, increased genera, Ruminococcus torques and Collinsella , may mitigate neuroinflammation in the substantia nigra by increasing secondary bile acids