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You should also make an appointment with your doctor if: You have a persistent fever or night sweats Pain that wakes you up at night You have had persistent pain for more than three days If you are feeling ill or unwell Pain is not relieved by pain medications Pain has not improved after two weeks of home treatment You have unexplained joint pain that does not go away Seek immediate medical treatment if: Your joints are stiff for more than 30 minutes after waking up Joint swelling occurs suddenly There is a joint deformity You have severe joint pain You have experienced a serious injury The joint is completely immobile Joint Pain Diagnosis Your doctor will take your personal medical and family history and do a physical examination