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The multiple pharmacological treatment options will enhance clinicians ability to identify effective personalised regimens by trying a second medication or combining medications with synergistic or complimentary actions or even escalating treatment to bariatric surgery based on patient preference and underlying comorbidities [7]

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The standard dosage and titration schedule for semaglutide for weight loss is as follows: Starting dose: 0.25 mg once a week Titration: Increase the dose by 0.25 mg every 4 weeks until reaching the target maintenance dose of 2.4 mg once a week Maintenance dose: 2.4 mg once a week Semaglutide is most effective when used in conjunction with a reduced-calorie diet and increased physical activity

But the prior authorization requirement and plan participation details mean you need to be proactive not reactive