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DOI: 10.70322/fibrosis.2026.10001 1

Insurers typically require: BMI 30 (or 27 with comorbidities like diabetes, hypertension) Documentation of lifestyle interventions (diet, exercise) tried first Sometimes a letter of medical necessity from the prescriber Some plans impose quantity limits (e.g., initial 30-day supply only) to monitor adherence before approving refills

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Individuals with certain HLA-DR gene variants have immune systems thatre structurally less able to recognize and clear biotoxins, making them significantly more vulnerable to the systemic effects of mycotoxin accumulation