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However, TRPA1 and TRPV4 antagonist treatments induced decrease on the allodynia and oxidative stress in the mice (Materazzi et al., 2012)

[DOI] [PubMed] [Google Scholar] 171.Blaszczyk R.T., Gorlo A., Dukacz M., Konopka A., Glowniak A

doi:10.1074/jbc.M206374200

In fact, mice with hepatocyte-specific DPP-4 knockdown have a significant reduction in serum DPP-4 activity and reduced adipose tissue inflammation, insulin resistance, and glucose intolerance [20]