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Menstrual and Fertility Implications: What the Clinical Evidence Shows Clinical trials and observational data report menstrual irregularities in 15-30% of women starting GLP-1 therapy, with most changes occurring within the first 3 months

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57 A high toxicity line also exists parallel to the probable toxicity line, and this begins at 300 g/mL at 4 hours, equating to a 90% incidence of severe hepatotoxicity and 24% mortality

Data on the number of people in the US taking glucagon-like peptide-1 medications, both to reduce obesity and to help control diabetes, show a somewhat stable trend