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This is to: a) rule out underlying issues

Moreover, glutamine-induced activation of mTORC1 results in the phosphorylation of the enzyme complex called carbamoyl phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase (CAD), which catalyzes the condensation reaction converting glutamine-derived nitrogen into the pyrimidine precursor orotate 34,35

NAC deacetylates under the action of N-deacetylase to enhance intracellular Cys, thereby increasing the endogenous synthesis of GSH

GBA1 mutations lead to reduced GCase activity, causing glucocerebroside to accumulate in lysosomes, thereby affecting lysosomal function, obstructing the autophagolysosomal pathway, and impairing the effective degradation of -syn aggregates [289]