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Potassium bicarbonate is strategically added to stabilize the active ingredient, prevent oxidation, and improve flavour

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Bioinformatics analysis, including hierarchical cluster, gene ontology, pathway, and network, was performed using Blast2GO (Version 3.5.0), the online Kyoto Encyclopedia of Genes and Genomes (KEGG) database ( and the InAct molecular interaction database ( Differentially expressed proteins between the two groups were screened using fold change method (2 fold)

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When NNMT activity is elevated as documented in obese adipose tissue, several cancer types, and aged skeletal muscle intracellular NAD+ availability decreases, SAM availability decreases, and downstream sirtuin activity (particularly SIRT1 and SIRT3) is reduced

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