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found that compared to benign prostate glands, PCa epithelial cells show significantly decreased LPAR1 mRNA but increased LPAR3 mRNA, suggesting a receptor expression switch potentially associated with disease progression and androgen independence (66)
REDEFINE 2, focused on type 2 diabetes, showed a mean 13.714.25% body weight reduction over 68 weeks with CagriSema compared to roughly 3% with placebo
SLC25A32 is the mitochondrial carrier for the tetrahydrofolate (THF) species in mitochondrial one-carbon (1 C) metabolism, as demonstrated by in vitro studies 23 , mouse genetics 24 and cell culture characterization 25,26,27
Merino-Ramrez M, Bolton CF
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