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Medical Criteria for Case Eligibility Gastroparesis, literally meaning stomach paralysis, is a chronic neuromuscular disorder characterized by delayed gastric emptying without evidence of mechanical obstruction, where the stomachs normal coordinated muscle contractions (peristalsis) become impaired or cease functioning entirely

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SNAC protects against proteolytic degradation of semaglutide molecules in the gastrointestinal tract through a localised increase in pH, and facilitates semaglutide absorption across the gastric epithelium primarily via the transcellular route [8]