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Practical Implications of No IGF-1 Elevation: The absence of IGF-1 stimulation makes AOD-9604 suitable for populations who need to avoid IGF-1 elevation, including individuals with personal or family history of hormone-sensitive cancers, those concerned about accelerated aging through growth pathway activation, people seeking fat loss without anabolic muscle-building effects, individuals who have contraindications to growth hormone therapy, and those undergoing screening or monitoring where IGF-1 elevation would be problematic

It is characterized by its stability in gastric environments and its influence on nitric oxide signaling and gene expression associated with vascular and immune function

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While these findings have generated significant interest, human studies remain limited, making it difficult to draw definitive conclusions about its clinical benefits