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Advances in molecular biology, immunology, and microbiome technologies have enabled substantial breakthroughs in IBD pathogenesis research

And as with all things in this space, source quality matters

First, the quality of the PCOS GLP-1 evidence is generally moderate to low: trials are small, short, heterogeneous in design and comparator, and often use surrogate rather than hard reproductive endpoints, so even the class with actual PCOS data is not on firm regulatory footing for this use