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Five of those (CJC-1295, Ipamorelin, Thymosin Alpha-1, AOD-9604, and Selank) are moving through the FDA's formal review process
Abbreviations ABCG2 ATP-binding cassette transporter G2 Akt Protein kinase B AMPK AMP-activated protein kinase BMP4 Bone morphogenetic protein 4 cAMP Cyclic adenosine monophosphate cas-3 Caspase-3 CDK2 Cyclin-dependent kinase 2 c-Myc Myelocytomatosis oncogene CRC Colorectal cancer CREB CAMP-response element binding protein DPP-4 Dipeptidyl peptidase IV E-cad E-cadherin ECM Extracellular matrix EGFR Epidermal growth factor receptor ENZ Enzalutamide EMT Epithelial-mesenchymal transition ERK Extracellular signal-regulated kinase Ex-4 Exendin-4 FGFR Fibroblast growth factor receptor GIP Glucose-dependent Insulinotropic Polypeptide GLP-1 Glucagon-like peptide-1 GLP-1RAs Glucagon-like peptide-1 receptor agonists GPCR G-protein-coupled receptor GSK3 Glycogen Synthase Kinase 3 HPV-16E7 Human papillomavirus type 16 E7 protein ICAM-1 Intercellular adhesion molecule-1 IGF Insulin-like growth factor IL Interleukin LC3I/II Microtubule-associated proteins light chain 3I/II LNG-IUD Levonorgestrel-releasing intrauterine device MAPK Mitogen-activated protein kinases MMP Matrix metalloproteinase mTOR Mammalian target of rapamycin NAFLD Non-alcoholic fatty liver disease NASH Non-alcoholic steatohepatitis NETs Neutrophil extracellular traps NF-B Nuclear factor kappa B PGR Progesterone receptor PI3K Phosphatidylinositol-4,5-bisphosphate 3-kinase PKA Protein kinase A PSC Pancreatic stellate cell RCTs Randomized controlled trials RhoA Rho-associated kinase ROS Reactive oxygen species S6K1 Ribosomal s6 kinase 1 SDF-1 Stromal cell-derived factor-1 SGLT2 Sodium-dependent glucose transporters 2 SKP2 S-phase kinase-associated protein-2 STAT3 Signal transducer and activator of transcription 3 T2DM Type 2 diabetes mellitus TGF- Transforming growth factor-beta TIMP Tissue inhibitor of metalloproteinase TNF- Tumor necrosis factor-alpha TZD Thiazolidinediones VCAM-1 Vascular cell adhesion molecule-1 VEGF Vascular endothelial growth factor Authors contributions Writing-original draft, A.Q.L., Y.X.D., Z.R.L., A.M.J., Z.Q.L., W.Z.H., C.Q., J.Z., P.L
Accin sobre el sistema inmunitario El GSH es un cofactor esencial en muchas acciones del sistema inmunitario
Biochim Biophys Acta (2009) 1790(11):145362
