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Similarly, frequently misused prescription medications like opioid painkillers can cause arrhythmia, low blood pressure, and heart failure and are the fastest-rising cause of emergency visits

Arch Toxicol 90(1):137

Several commenters stated that removing the adjustment, particularly retroactively 9 months into the reporting period, would create harm by making it more difficult for ACOs serving high proportions of dual eligible and Medicare Part D LIS beneficiaries to remain in the Shared Savings Program