While that initial boost is great, the real goal is to maintain your B12 levels over time so you can enjoy sustained energy and focus without the ups and downs
Vitamin B12 deficiency can also be found in people with poor nutrition, pernicious anemia, infection, cancer, surgery, alcohol, medications (PPIs or other acid-suppressing drugs), exposure to nitrous oxide (during surgery or recreational use), stomach/intestinal problems such as intestinal dysbiosis, leaky gut or gut inflammation, atrophic gastritis or hypochlorhydria (low stomach acid) and/or nerve damage
Sources: Hangovers - Symptoms and causes | The Mayo Clinic Drug Bioavailability - StatPearls | NCBI Bookshelf
If you've been taking high doses for months, it's smart to check your levels once in a while