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Innate immune cell death in neuroinflammation and Alzheimers disease

The location of Cu B is better conserved than that of Cu A , which is in agreement with the previous observations [12,26,31] as well as with the recently elucidated crystal structure of Zn(II)-bound TRP1 [25]

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A deeper understanding of these interconnected metabolic networks clarifies the critical role of ferroptosis in OA progression and lays a robust foundation for integrated therapeutic strategies targeting both metabolic reprogramming and ferroptosis