Bariatric surgery (including gastric bypass via Roux-en-Y or blind-loop intestinal bypass): Multifactorial, including systemic catabolism, steroid, tacrolimus, nutritional deficiencies (e.g., carnitine) investigation & monitoring investigation & monitoring interpreting the NH3 level This is discussed below in the treatment section
Geiser JS, Heathman MA, Cui X, Martin J, Loghin C, Chien JY, et al
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Additionally, FSP1 inhibitors, as novel non-GPX4-dependent targeted agents, have demonstrated potential to overcome drug resistance in prospective studies of breast cancer and non-small cell lung cancer (131)
