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Based on this evidence, multidisciplinary guidelines have listed GLP 1RAs as first - line or preferred treatment options for patients with type 2 diabetes and/or obesity with high cardiovascular risk [51, 52]

There was no significant difference in endothelial-independent vasorelaxation to increasing doses of sodium nitroprusside, or in the maximal relaxation between vessels from PF- or AF-FMT cohorts (Fig