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4.1 Enzymatic mechanisms 4.1.1 The glutathione (GSH)-GPX4 axis Ferroptosis is characterized by the hallmark feature of intracellular lipid peroxide accumulation, with the glutathione-glutathione peroxidase 4 (GSH-GPX4) axis playing a pivotal role in suppressing lipid peroxidation

Gut microbiota dysbiosis is linked to higher risk of mental health condition and psychiatric diseases (118, 119)

Both alcohol and fluoxetine reshaped the gut microbiota, but their combination produced the most pronounced changes

According to a 2005 study, 5% of American women and 12% of men will develop a kidney stone at some time in their life, and prevalence has been rising in both sexes.[ref] Urinary crystals can also form in urine that contains calcium and oxalates