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coli or yeast cells produce a fusion protein that is enzymatically cleaved to release the peptide) ( [41] ) ( [40] )

In line with our short-term metabolic analyses, previous studies in New Zealand obese and diet-induced obese male mice suggested that GLP1/E acts primarily at central levels to reverse metabolic alterations by decreasing food intake and body weight, while the potential beneficial effects on pancreatic beta-cells were possibly secondary and indirectly-mediated 33,48

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Similarly, GLP-1 medications in general are not recommended during breastfeeding