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The use of non-approved peptides or the use of approved peptides for conditions other than what they were approved for is known as "off-label" use

Immunotherapy approaches are being evaluated for their potential use in Stage 1 (2 islet autoantibodies but normoglycaemia) or Stage 2 (autoantibodies and dysglycaemia) type 1 diabetes to prevent Stage 3 clinical type 1 diabetes, and for the preservation of beta cell function before and shortly after onset of Stage 3 clinical type 1 diabetes [290]

Renal function should be assessed before starting treatment and monitored regularly, particularly during illness or dehydration

Theocharidis, G