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Closely related to oxidative stress is the so-called dicarbonyl stress, i.e., the accumulation of dicarbonyl metabolites leading to cell and tissue disfunction (40)

This activation of the NRF2/SLC7A11/GPX4 pathway enhanced GSH levels, decreased lipid ROS accumulation, inhibited ferroptosis and lipid peroxidation, and improved the cognitive functions of AD mice ( In summary, Ghrelin, Neuritin, GAA, and Artemisinin may mitigate cerebral neuronal injury and cognitive dysfunction by modulating neuronal ferroptosis, lipid peroxidation, the antioxidant system, oxidative stress, mitochondrial dysfunction, and neuroinflammation

When skin expands or shrinks rapidly, collagen and elastin the main proteins that make up the structure of our skin can break apart

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