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Since the pancreas has abundant GAD, a direct immunological destruction occurs in the pancreas and the patients will have diabetes mellitus

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243 PKC also affects guanosines regulatory effects on glial cells, reducing their viability and increasing oxidative damage

Some, but not all, observational studies have found that elderly individuals with lower status of folate and/or vitamin B 12 may have poorer memory performance, especially episodic memory (i.e., memory of events, times, and places) (108-111)