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10.1146/annurev-biochem-061516-045037 148 TakanoT
Introduction Peptides represent an expanding class of biologically active molecules that bridge the gap between small molecules and larger biotherapeutics
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Key physiological effects: Stimulates pituitary gene transcription of hGH messenger RNA Promotes episodic hormone release patterns Maintains natural feedback mechanisms through somatostatin interaction Preserves growth hormone neuroendocrine axis function [14] Sermorelin may be prescribed to children to treat growth hormone deficiency and, in specific circumstances, to adults as determined by a licensed healthcare provider
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