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In a renal proximal tubule-specific Tsc1 gene-knockout mouse model, downregulated AMPK phosphorylation was observed in the enlarged kidneys, which also exhibited aberrant proliferation of proximal tubule cells, renal interstitial inflammation, and fibrosis

Lidocaine clearance has been used to assess liver transplant function, but its use is limited by the effect of hypoperfusion (as occurs in sepsis or volume depletion)

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PMID: 41500989 G6PD activator AG1 purchased from MedChemExpress