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In one study, dysbiosis in individuals exposed to chronic stress was linked to increased intestinal permeability, also known as leaky gut. This permeability allows bacterial endotoxins to enter the bloodstream, promoting systemic inflammation

Myalgic encephalomyelitis/chronic fatigue syndrome in the era of the human microbiome: persistent pathogens drive chronic symptoms by interfering with host metabolism, gene expression, and immunity

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Lei S, Rossi S, Huang B (2022) Metabolic and physiological regulation of aspartic acid-mediated enhancement of heat stress tolerance in perennial ryegrass